Thymosin Alpha-1

Compound background

Thymosin α-1 is a 28-amino-acid thymic peptide that serves as an immune modulator: by binding Toll-like receptors 2 and 9 on dendritic and other innate immune cells, it enhances antigen presentation, expands CD4⁺/CD8⁺ T- and NK-cell activity, elevates interferon-γ and IL-12 while damping excess TNF-α and IL-1β, and up-regulates MHC-I expression—sharpening antiviral and antitumor defenses without provoking cytokine storm. Clinically licensed in many countries to support treatment of chronic hepatitis B/C and to bolster vaccine responses in immunocompromised hosts, it is now being investigated as an adjunct to checkpoint inhibitors in cancer, as a lymphocyte-restoring therapy in severe viral infections (e.g., COVID-19), and as a sepsis modulator, where benefits appear to depend on timing and patient selection. Overall, accumulated evidence depicts thymosin α-1 as a homeostatic “immune re-balancer” that nudges innate sensors so adaptive immunity can self-correct, offering broad therapeutic potential with a favorable safety profile.

Quality standards

  • Greater than 99% pure
  • Endotoxin-free
  • Sterility guaranteed
  • No detectable levels of heavy metals

Sourcing standards

  • Raw ingredients manufactured by an FDA registered & audited supplier following cGMP standards
  • Finished peptides 0.22 µm sterile-filtered (aseptically processed) & produced in a GMP facility
  • Tested by a US FDA registered & audited third-party analytical lab accredited by ISO/IEC and U.S. Department of Ecology

Analytical reports

Batch 1356 – Thymosin Alpha 1 99.41 11.86mg

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Structure & Specification

Thymosin Alpha-1 Peptide Summary

Product Specifications: 12mg Lyophilized Powder (>99% purity) in 3ml vial.

*Requires Reconstitution with solvent such as BAC Water (Sold Here)

Appearance: Solid, white powder in 3mL glass ampule

Chemical Formula: C129H215N33O55

PubChem CID: 16130571

CAS Number: 62304-98-7

Molecular Weight: 3108.31 g/mol

Storage: Store at ≤6°C, sealed, away from heat, light, and moisture.

Concentration: ≥99%

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At every step, we prioritize quality by conducting rigorous third-party testing on all our products. These tests focus on four key characteristics—identity, purity, sterility, and endotoxicity—ensuring that each batch meets the highest standards for safety and performance, with independent third-party Certificates of Analysis (COAs) to verify our commitment to excellence.

1

Identity Test

Identity testing ensures that the product contains the correct ingredient as labeled, verifying its authenticity and matching it to established reference standards.

2

Purity Test

Purity and concentration testing verifies that the ingredient is present in the correct amount, with a purity of 98% or higher to meet stringent quality standards.

3

Sterility Test

Sterility testing ensures that the product is completely free from bacteria, fungi, and other microorganisms.

4

Endotoxicity

Endotoxicity testing specifically detects and quantifies lipopolysaccharides (LPS), components of bacterial cell walls, to ensure the product is free from harmful endotoxins.

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