MOTS-c
$39.00
MOTS-c is a 16-amino-acid mitochondrial-derived peptide (Met-Arg-Trp-Gln-Glu-Val-Val-Lys-Lys-Gly-Arg-Leu-Ser-Phe-Ser-Gly) encoded within the 12S-rRNA region of mitochondrial DNA. In cell and animal models it acts as a rapid “metabolic stress signal,” translocating to the nucleus and activating AMPK-linked transcription programs that favor glucose uptake, fatty-acid oxidation and antioxidant defense.
Recent mechanistic work shows MOTS-c binds and stimulates protein-kinase CK2, a target that helps explain its ability to preserve skeletal-muscle insulin sensitivity and endurance capacity in rodents subjected to metabolic stress. The first human analogue, CB4211, completed Phase 1a/1b testing in adults with obesity and NAFLD, where four weeks of daily sub-cutaneous dosing was well-tolerated and produced double-digit relative reductions in liver fat versus placebo.
Quality standards
- Greater than 99% pure
- Endotoxin-free
- Sterility guaranteed
- No detectable levels of heavy metals
Sourcing standards
- Raw ingredients manufactured by an FDA registered & audited supplier following cGMP standards
- Finished peptides 0.22 µm sterile-filtered (aseptically processed) and produced in a GMP facility
- Tested by a US FDA registered & audited third-party analytical lab accredited by ISO/IEC and U.S. Department of Ecology
Analytical reports
Structure & Specification
MOTS-C Peptide Summary
Product Specifications: 10mg Lyophilized Powder (>99% purity) in 3ml vial.
*Requires Reconstitution with solvent such as BAC Water (Sold Here)
Application: Research peptide evaluated for potential metabolic regulatory and cognitive properties.
Chemical Formula: C101H152N28O22S2
PubChem CID: 146675088
CAS Number: 1627580-64-6
Molecular Weight: 2174.6 g/mol
Synonyms: MOTS-c, Mitochondrial-Derived Peptide, MDP
Storage: Store at ≤25°C, sealed, away from heat, light, and moisture.
Concentration: ≥99%
Disclaimer: This product is intended solely for laboratory research purposes. It is not suitable for consumption by humans, nor for medical, veterinary, or household purposes. Researchers should handle MOTS-C with care and adhere to strict safety guidelines during experiments. Kindly review our Terms & Conditions before making a purchase. *
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At every step, we prioritize quality by conducting rigorous third-party testing on all our products. These tests focus on four key characteristics—identity, purity, sterility, and endotoxicity—ensuring that each batch meets the highest standards for safety and performance, with independent third-party Certificates of Analysis (COAs) to verify our commitment to excellence.
Identity Test
Identity testing ensures that the product contains the correct ingredient as labeled, verifying its authenticity and matching it to established reference standards.
Purity Test
Purity and concentration testing verifies that the ingredient is present in the correct amount, with a purity of 98% or higher to meet stringent quality standards.
Sterility Test
Sterility testing ensures that the product is completely free from bacteria, fungi, and other microorganisms.
Endotoxicity
Endotoxicity testing specifically detects and quantifies lipopolysaccharides (LPS), components of bacterial cell walls, to ensure the product is free from harmful endotoxins.
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