IGF-1 LR3

Compound background

IGF-1 LR3 is a 83-amino-acid analog of insulin-like growth factor 1 engineered by (1) extending the native 70-residue sequence with a 13-residue N-terminal peptide and (2) replacing the third amino acid with arginine. These changes reduce its affinity for IGF-binding proteins and protect it from rapid enzymatic cleavage, prolonging plasma half-life from ~10 min to 6โ€“10 h. Freed from most carrier constraints, IGF-1 LR3 more readily engages IGF-1 receptors (and, to a lesser extent, insulin receptors), triggering the canonical PI3K-Akt-mTOR and MAPK/ERK pathways that drive glucose uptake, protein synthesis, mitosis, and tissue remodeling.

Quality standards

  • Greater than 99% pure

Sourcing standards

  • Raw ingredients manufactured by an FDA registered & audited supplier following cGMP standards
  • Finished peptides 0.22 ยตm sterile-filtered (aseptically processed) and produced in a GMP facility
  • Tested by a US FDA registered & audited third-party analytical lab accredited by ISO/IEC and U.S. Department of Ecology

Learn more about Peptidology product sourcing, testing and quality standards.

Analytical reports

Batch 1358 – IGF-LR3 99.75% 1.22mg

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At every step, we prioritize quality by conducting rigorous third-party testing on all our products. These tests focus on four key characteristicsโ€”identity, purity, sterility, and endotoxicityโ€”ensuring that each batch meets the highest standards for safety and performance, with independent third-party Certificates of Analysis (COAs) to verify our commitment to excellence.

1

Identity Test

Identity testing ensures that the product contains the correct ingredient as labeled, verifying its authenticity and matching it to established reference standards.

2

Purity Test

Purity and concentration testing verifies that the ingredient is present in the correct amount, with a purity of 98% or higher to meet stringent quality standards.

3

Sterility Test

Sterility testing ensures that the product is completely free from bacteria, fungi, and other microorganisms.

4

Endotoxicity

Endotoxicity testing specifically detects and quantifies lipopolysaccharides (LPS), components of bacterial cell walls, to ensure the product is free from harmful endotoxins.

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