Repair Signaling
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May 1st
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Peptidology Research Faculty
GHK-Cu Research Peptide: A Molecular Spark for Tissue Renewal
Origins & Discovery The tripeptide glycyl-L-histidyl-L-lysine (GHK) was isolated from human plasma in 1973 when Pickart observed that young serum “caused old liver tissue to produce proteins more characteristic of younger individuals.” Its high affinity for Cu²⁺ rapidly forms the chelate now known as GHK-Cu, which occurs naturally in plasma, saliva, and urine. Concentrations decline […]
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April 30th
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Peptidology Research Faculty
BPC-157 Research Peptide: Molecular Pathways and Healing Insights
Origins, Chemistry & Structural Biology BPC-157 (Body Protection Compound 157) is a 15-mer fragment (GEPPPGKPADDAGLV) originally isolated from human gastric juice and highly conserved across mammals. Its 1 414 Da mass and amphipathic profile confer remarkable aqueous stability—even in gastric acid—which in turn underpins wide laboratory utility. Structure–activity modelling reveals multiple proline clusters that resist […]